Stora Enso and Cypak, who are a company specialising in smart electronics, have developed a unique pharmaceutical folding carton system called the Discreet Dose Slider (DDS) and a “smarter” version is called the DDSi. The systems are designed to effect improved patient compliance and to enable doctors to improve monitoring the effectiveness and effects of drugs on individual patients.
The systems are based on a special cartonboard substrate developed by Stora Enso that incorporates smart sensors (silicon chips called Application Specific Integrated Circuits or ASICs) developed by Cypak. The cartons can be made in a wide range of sizes at high speed on existing cartoning equipment with only minor changes in tooling. They incorporate a “smart” inner design for filling unit dose pharmaceutical packs like fold-over blisters or push-through blisters.
Firstly, both systems provide a lot of space for conveying both statutory and other important data on the product for patient guidance. The DDSi incorporates sensors, printed one per pocket in the inlay using conductive inks. The electronic circuit is broken whenever the patient removes the product (a pill, tablet or capsule) and a beeper continues to sound until the patient presses a separate button within a questionnaire panel to record how they are feeling or any reaction to the product along with the time.
Once a course of medication is completed, the pack is taken back to the doctor who links it to a PC, which downloads the data recorded on the ASIC chip built into the inlay of the carton. Alternatively, Cypak can supply a reader that can SMS or e-mail the recorded data on the carton to healthcare personnel. Optionally, the carton can include an acoustic signal that reminds the patient to take the medicine. The DDSi carton can be especially useful to track clinical trials. |